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What is Uthever®︎? 

Uthever® from EffePharm is a powerful NAD+ precursor that has been extensively researched in both human and animal scientific studies, with over 20 publications validating its efficacy. Some of the best studied areas are its use in anti-ageing, skin health, gut health, sports performance, pneumonia and rare diseases. The health benefits in these areas are observed in children and adults, under health conditions and various medical conditions.

​In a 60-day clinical study, we tested Uthever® NMN on 66 participants and observed notable increases in NAD+ levels, walking endurance, and overall quality of life.*

Results of the Uthever® NMN Clinical Trial

The aim of the clinical study is to investigate the safety and efficacy of Uthever® NMN, the first branded NMN ingredient. In addition, narrowing in on the anti-ageing impact of Uthever® NMN, it was assessed through parameters like pulse pressure and blood pressure normalisation.

For the safety evaluation, the study found no clinically significant safety concerns, with no adverse side effects observed. Beyond that, EffePharm’s clinical trial unveiled promising results as the Uthever® group displayed notable improvements in these parameters compared to the placebo group.

In terms of efficacy, the Uthever® group exhibited a trend of improvement in cellular blood NAD+/NADH, six-minute walking endurance, SF-36, and HOMA IR index compared to the placebo group.

1. Blood Cellular NAD+/NADH

Specifically, the Uthever® group showed an 11.3 percent increase in NAD+/NADH levels at day 30 and a remarkable 38 percent increase at day 60, compared to the placebo group’s 14.3 percent rise

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2. 6-Minute Walking Endurance Test

Walking endurance also demonstrated a positive effect, with a 6.5 percent increase in the Uthever® group at day 60, while the placebo group remained unchanged.

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3. SF-36

Similarly, the SF-36 questionnaire, which serves as an indicator of subjects’ overall well-being, indicated enhanced well-being in the Uthever® group at day 60, showing almost double the increase compared to the placebo group.
side effects

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